Hydnum repandum
The hedgehog mushroom, Hydnum repandum L.
Credit: Pau Cabot
Source: Wikimedia common
Classification
Kingdom Fungi
Phylum Basidiomycota
Class Basidiomycetes
Order Cantharellales
Family Hydnaceae
Genus Hydnum
Dentinum repandum (L.) Gray
Dentinum rufescens (Schaeff.) Gray
Fungus erinaceus Vaill.
Hydnum album Pers.
Hydnum aurantium Raf.
Hydnum bicolor Raddi
Hydnum bulbosum Raddi
Hydnum clandestinum Batsch
Hydnum diffractum Berk.
Hydnum flavidum Schaeff.
Hydnum medium Pers.
Hydnum pallidum Raddi
Hydnum rufescens Schaeff.
Hydnum washingtonianum Ellis & Everh.
Hypothele repanda (L.) Paulet
Sarcodon abietinus R. Heim [as 'abietinum']
Sarcodon repandus (L.) Quél.
Tyrodon repandus (L.) P. Karst.
Hedgehog mushroom
Kanoshita (Japanese)
Cap: 3-10 cm diameter, convex, becoming nearly plane, disc sometimes depressed; margin inrolled at first, lobed to undulate; surface dry, smooth to slightly scaly, cream to buff-orange, bruising to orange-brown.
Flesh: thick, white, brittle, bruising buff-orange, crumbly; odor and taste mild.
Hymenophore: spines 0.2-0.6 cm long, brittle, cream-colored, bruising orange-brown, sometimes decurrent.
Stem: 2-7 cm tall, 1.5-2.5 cm thick, equal to enlarged at the base; attachment central to eccentric; surface dry, smooth, cream to buff-yellow, bruising orange-brown; veil absent.
Spores: 6-9 x 5.5-7 µm, hyaline, nearly round, smooth.
Spore print: white.
Habitat: scattered to gregarious under conifers or occasionally with hardwoods.
A cytotoxic diepoxide named repandiol ((2R,3R,8R,9R)-4,6-decadiyne- 2,3:8,9-diepoxy-1,10-diol, see below) was isolated from a methanol extract of Hydnum repandum fruit bodies (Takahashi et al., 1992).
Antitumor effects
An extract of the culture mycelia showed 70% inhibition against Sarcoma 180 solid cancer in mice, while extracts from the fruit bodies showed 90% inhibition against both Sarcoma 180 and Ehrlich solid cancer in mice (Ohtsuka et al., 1973). Furthermore, the compound repandiol described above showed potent cytotoxic activity against a variety of tumor cell types, especially colon adenocarcima cells, for which its IC50 is 0.30 (Takahashi et al., 1992).
In a study of antimicrobial activity using the disk-diffusion method, it was shown that a chloroform extract of the hedgehog mushroom had mild antibiotic activity against Enterobacter aerogenes, Staphylococcus aureus, Staphylococcus epidermidis and Bacillus subtilis, while the ethanol extract had mild activity against only Bacillus subtilis (Yamach and Bilgili, 2006).
Links
References
Ohtsuka S, Ueno S, Yoshikumi C, Hirose F, Ohmura Y, Wada T, Fujii T, Takahashi E.
Polysaccharides having an anticarcinogenic effect and a method of producing them from species of Basidiomycetes.
UK Patent 1331513, 26 September 1973.
Takahashi A, Endo T, Nozoe S.
Repandiol, A new cytotoxic diepoxide from the mushrooms Hydnum repandum and H. repandum varalbum.
Chem Pharm Bull. 1992 40(12):3181-4.
Yamach M, Bilgili F.
Antimicrobial activities of fruit bodies and/or mycelial cultures of some mushroom isolates
Pharm Biol. 2006 44(9):660-7.
Last modified: 17-Aug-2008
August 5th, 2012 at 10:27 pm
[...] taken at Bastion Cascades, Tas and in victorian locations incl. Sherbrooke forest. According to medicinal mushrooms(a succinct, well referenced amateur website by Robert Sasata) the compound repandiol isolated from [...]